Home > Product > Antibody > Rabbit Anti-GADD45G/FITC Conjugated antibody
GADD45 gamma; Cytokine responsive protein CR6; Cytokine-responsive protein CR6; DDIT-2; DDIT2; DNA damage-inducible transcript 2 protein; GA45G_HUMAN; Gadd45g; GADD45G; Growth arrest and DNA damage inducible gamma; Growth arrest and DNA damage-inducible p
Cat:
SL7069R-FITC
Species Reactivity:
Mouse,Rat,(predicted: Human,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human GADD45 gamma
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
17kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.

Function:
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.

Subunit:
Interacts with GADD45GIP1.

Similarity:
Belongs to the GADD45 family.

Database links:

Entrez Gene: 504939 Cow

Entrez Gene: 10912 Human

Entrez Gene: 291005 Rat

Omim: 604949 Human

SwissProt: Q2KIX1 Cow

SwissProt: O95257 Human

SwissProt: Q9WTQ7 Rat

Unigene: 9701 Human

Unigene: 16950 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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