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Rabbit Anti-GADD45G/FITC Conjugated antibody
background:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Function:
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Subunit:
Interacts with GADD45GIP1.
Similarity:
Belongs to the GADD45 family.
Database links:
Entrez Gene: 504939 Cow
Entrez Gene: 10912 Human
Entrez Gene: 291005 Rat
Omim: 604949 Human
SwissProt: Q2KIX1 Cow
SwissProt: O95257 Human
SwissProt: Q9WTQ7 Rat
Unigene: 9701 Human
Unigene: 16950 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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