background:
PEF1 (penta-EF hand domain containing 1) is a Ca(2+)-binding protein that belongs to the penta-EF hand family which shares similarities to the apoptosis linked gene ALG-2. PEF1 heterodimerizes with PDCD6/ALG2 and dissociates from PDCD6/ALG2 in the presence of Ca(2+).
Subunit:
Heterodimer; heterodimerizes with PDCD6. Dissociates from PDCD6 in presence of Ca(2+).
Subcellular Location:
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated in the presence of Ca(2+).
Similarity:
Contains 5 EF-hand domains.
Database links:
Entrez Gene: 553115 Human
Entrez Gene: 67898 Mouse
Entrez Gene: 297900 Rat
Omim: 610033 Human
SwissProt: Q9UBV8 Human
SwissProt: Q8SFY6 Mouse
SwissProt: Q641Z8 Rat
Unigene: 470417 Human
Unigene: 20818 Mouse
Unigene: 96097 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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