Home > Product > Antibody > Rabbit Anti-DUSP22/FITC Conjugated antibody
Dual specificity protein phosphatase 22; JNK stimulatory phosphatase 1; JSP 1; JSP1; LMW DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; Mitogen activated protein kinase phosphatase x; MKPX; DUS22_HUMAN.
Cat:
SL7066R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human DUSP22/JSP1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
21kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase /c-Jun N-terminal kinase (SAPK/JNK)

Function:
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity).

Subunit:
Monomer.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.

Post-translational modifications:
Myristoylation regulates subcellular location, and is necessary for activation of JNK.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain.

Database links:

Entrez Gene: 56940 Human

Entrez Gene: 105352 Mouse

Entrez Gene: 361242 Rat

SwissProt: Q9NRW4 Human

SwissProt: Q99N11 Mouse

Unigene: 29106 Human

Unigene: 289646 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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