background:
NT5C1A dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. It helps to regulate adenosine levels in the heart during ischemia and hypoxia.
Function:
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.
Similarity:
Belongs to the 5'-nucleotidase type 3 family.
Database links:
Entrez Gene: 84618 Human
Entrez Gene: 230718 Mouse
Omim: 610525 Human
SwissProt: Q9BXI3 Human
SwissProt: A3KFX0 Mouse
Unigene: 307006 Human
Unigene: 354635 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|