background:
Fatty acid elongase specific to C12-C16 saturated and monoinsaturated fatty acids.
Function:
Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16:0 acyl-CoAs.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Ubiquitous.
Post-translational modifications:
N-Glycosylated.
Similarity:
Belongs to the ELO family.
Database links:
Entrez Gene: 79071 Human
Entrez Gene: 170439 Mouse
Entrez Gene: 171402 Rat
Omim: 611546 Human
SwissProt: Q9H5J4 Human
SwissProt: Q920L5 Mouse
SwissProt: Q920L6 Rat
Unigene: 412939 Human
Unigene: 314113 Mouse
Unigene: 46942 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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