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Rabbit Anti-BTG1/FITC Conjugated antibody
background:
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
Function:
Anti-proliferative protein.
DISEASE:
Note=A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC.
Similarity:
Belongs to the BTG family.
Database links:
Entrez Gene: 694 Human
Entrez Gene: 12226 Mouse
Entrez Gene: 29618 Rat
Omim: 109580 Human
SwissProt: P62324 Human
SwissProt: Q6IBC8 Human
SwissProt: P62325 Mouse
SwissProt: Q63073 Rat
Unigene: 255935 Human
Unigene: 1000 Mouse
Unigene: 23811 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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