Home > Product > Antibody > Rabbit Anti-BTG1/FITC Conjugated antibody
B cell translocation gene 1 protein; B cell translocation gene 1, anti proliferative; BTG1 protein; BTG1_HUMAN.
Cat:
SL7526R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human BTG1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
19kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]

Function:
Anti-proliferative protein.

DISEASE:
Note=A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC.

Similarity:
Belongs to the BTG family.

Database links:

Entrez Gene: 694 Human

Entrez Gene: 12226 Mouse

Entrez Gene: 29618 Rat

Omim: 109580 Human

SwissProt: P62324 Human

SwissProt: Q6IBC8 Human

SwissProt: P62325 Mouse

SwissProt: Q63073 Rat

Unigene: 255935 Human

Unigene: 1000 Mouse

Unigene: 23811 Rat

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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