Rabbit Anti-TCERG1/FITC Conjugated antibody

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CA 150; Co activator of 150 kDa; Coactivator of 150 kDa; MGC133200; TAF 2S; TAF2S; TATA box binding protein (TBP) associated factor RNA polymerase II S 150kD; TATA box binding protein associated factor 2S; TATA box binding protein associated factor RNA po

Cat:

SL1361R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TCERG1/CA150

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

124kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
CA150 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. It interacts with the hyperphosphorylated SLCterminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain.

Function:
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HISLV1) promoter.

Subunit:
Binds formin (By similarity). Binds RNA polymerase II, HD and SF1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Detected in brain neurons.

Similarity:
Contains 6 FF domains.

Database links:
UniProtKB/Swiss-Prot: O14776.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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