Rabbit Anti-THRSP/FITC Conjugated antibody

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Lpgp; LPGP1; S14; S14 protein; SPOT 14; Spot 14 protein; SPOT14; SPOT14 homolog; Thrsp; THRSP_HUMAN; Thyroid hormone inducible hepatic protein; Thyroid hormone responsive (SPOT14 homolog rat); Thyroid hormone responsive; Thyroid hormone responsive protein

Cat:

SL6738R-FITC

Species Reactivity：

Rat,(predicted: Human,Mouse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human THRSP

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

17kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.Mainly expressed in tissues that synthesize triglycerides.

Function:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.

Subunit:
Homodimer. Heterodimer with MID1IP1. Interacts with THRB and PLAGL1.

Subcellular Location:
Cytoplasm.Nucleus.

Tissue Specificity:
Mainly expressed in tissues that synthesize triglycerides.

Similarity:
Mainly expressed in tissues that synthesize triglycerides.
Belongs to the SPOT14 family.

Database links:

Entrez Gene: 7069 Human

Entrez Gene: 21835 Mouse

Entrez Gene: 25357 Rat

Omim: 601926 Human

SwissProt: Q92748 Human

SwissProt: Q62264 Mouse

SwissProt: P04143 Rat

Unigene: 591969 Human

Unigene: 28585 Mouse

Unigene: 81140 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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