Rabbit Anti-CDC37/FITC Conjugated antibody

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S cerevisiae hypothetical protein CDC37; CDC 37; CDC37; CDC37 cell division cycle 37 homolog; CDC37 cell division cycle 37 S cerevisiae homolog; Cdc37 homolog; CDC37 protein; CDC37_HUMAN; CDC37A; Cell division cycle 37 homolog; Hsp90 chaperone protein kin

Cat:

SL4290R-FITC

Species Reactivity：

Human,Mouse,(predicted: Rat,Dog,Pig,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human CDC37

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

42kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.

Function:
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.

Subunit:
Forms a complex with Hsp90/HSP90AB1 and CDK6. Interacts with AR, CDK4, CDK6, EIF2AK1 and RB1.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Constitutively sumoylated by UBE2I.

Similarity:
Belongs to the CDC37 family.

Database links:

Entrez Gene: 38232 Fruit fly (Drosophila melanogaster)

Entrez Gene: 11140 Human

Entrez Gene: 12539 Mouse

Entrez Gene: 114562 Rat

Omim: 605065 Human

SwissProt: Q24276 Fruit fly (Drosophila melanogaster)

SwissProt: Q16543 Human

SwissProt: Q61081 Mouse

SwissProt: Q63692 Rat

Unigene: 4857 Fruit fly (Drosophila melanogaster)

Unigene: 160958 Human

Unigene: 32331 Mouse

Unigene: 17982 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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