Rabbit Anti-VMAT1/FITC Conjugated antibody

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Adrenal chromaffin granule amine transporter; CGAT; CGAT; Chromaffin granule amine transporter; SLC18A1; Solute carrier family 18 (vesicular monoamine), member 1; Solute carrier family 18 member 1; VAT 1; VAT1; Vesicular amine transporter 1; VMAT 1; VMAT1

Cat:

SL6677R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human VMAT1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

58kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008].

Function:
Involved in the vesicular transport of biogenic amines.

Subcellular Location:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.

Similarity:
Belongs to the major facilitator superfamily. Vesicular transporter family.

Database links:

Entrez Gene: 10493 Human

Entrez Gene: 26949 Mouse

Omim: 604631 Human

SwissProt: Q99536 Human

SwissProt: Q62465 Mouse

Unigene: 514199 Human

Unigene: 29210 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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