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Rabbit Anti-HOXB5/FITC Conjugated antibody
background:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008].
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Location:
Nucleus.
Tissue Specificity:
Spinal cord.
Similarity:
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links:
Entrez Gene: 3215 Human
Entrez Gene: 15413 Mouse
Entrez Gene: 497987 Rat
Omim: 142960 Human
SwissProt: P09067 Human
SwissProt: P09079 Mouse
Unigene: 654456 Human
Unigene: 207 Mouse
Unigene: 229521 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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