Home > Product > Antibody > Rabbit Anti-HOXA9/FITC Conjugated antibody
ABD-B; Abd-B, drosophila, homolog of; D6a9; Homeobox protein A9; Homeobox 1G; Homeobox A9; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; Homeobox protein Hox-A9; Hox-1.7; Hox-1.7, mouse, homolog of; HOX1; Hox1.7; Hox1G; Hox1r5; Hoxa-9; Hoxa7; HOXA9/M
Cat:
SL6667R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human HOXA9
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
26, 30kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
HOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells. HOXA9 expression changes dramatically with age - a uniformly low level of expression during early adulthood is replaced by a frequently very high expression in adults over sixty.

Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 396096 Chicken

Entrez Gene: 100725915 Guinea pig

Entrez Gene: 645 Human

Entrez Gene: 15405 Mouse

Entrez Gene: 500126 Rat

Omim: 142956 Human

SwissProt: Q98924 Chicken

SwissProt: P51783 Guinea pig

SwissProt: P31269 Human

SwissProt: P09631 Mouse

Unigene: 659350 Human

Unigene: 4694 Mouse

Unigene: 203714 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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