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Rabbit Anti-HMPH/FITC Conjugated antibody
background:
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.
Function:
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity).
Subcellular Location:
Nucleus (Probable).
Tissue Specificity:
Liver and promyelocytic leukemia cell line HL60.
Similarity:
Contains 1 homeobox DNA-binding domain.
Database links:
Entrez Gene: 3087 Human
Entrez Gene: 15242 Mouse
Entrez Gene: 397232 Pig
Entrez Gene: 79237 Rat
Omim: 604420 Human
SwissProt: Q03014 Human
SwissProt: P43120 Mouse
Unigene: 118651 Human
Unigene: 33896 Mouse
Unigene: 12188 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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