Rabbit Anti-MTCBP1/FITC Conjugated antibody

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ADI 1; Adi1; Adi-1; ADI1 antibody; APL1; ARD; EC 1.13.; Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; MTCBP 1; MTCBP-1; MTCBP1; MTND_HUMAN; Ni-ARD;

Cat:

SL6507R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human MTCBP1/ADI1 (81-126aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

23kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
his gene encodes an enzyme that belongs to theaci-reductone dioxygenase family of metal-binding enzymes, whichare involved in methionine salvage. This enzyme may regulate mRNAprocessing in the nucleus, and may carry out different functionsdepending on its localization. Related pseudogenes have beendefined on chromosomes 8 and 20.

Function:
Catalyzes the formation of formate and2-keto-4-methylthiobutyrate (KMTB) from1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Alsodown-regulates cell migration mediated by MMP14. Necessary forhepatitis C virus replication in an otherwise non-permissive cellline.

Subunit:
Monomer (By similarity). Interacts with MMP14.

Subcellular Location:
Cytoplasm. Nucleus. Cell membrane;Peripheral membrane protein; Cytoplasmic side. Note=Localizes tothe plasma membrane when complexed to MMP14.

Tissue Specificity:
Detected in heart, colon, lung, stomach,brain, spleen, liver, skeletal muscle and kidney.

Similarity:
Belongs to the acireductone dioxygenase (ARD) family.

Database links:

UniProtKB/Swiss-Prot: Q08554.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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