background:
TUSC5 may be involved in fat metabolism. It is expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle and at lower levels in brain and lung. TUSC5 is strongly down regulated in lung cancer tissues, due to hypermethylation of the corresponding locus.
Function:
May be involved in fat metabolism
Subcellular Location:
Membrane; Multi-pass membrane protein
Tissue Specificity:
Expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle, and at lower levels in brain and lung. Strongly down-regulated in lung cancer tissues, due to hypermethylation of the corresponding locus.
Similarity:
Belongs to the CD225/Dispanin family.
Database links:
Entrez Gene: 286753 Human
SwissProt: Q8IXB3 Human
Unigene: 19259 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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