Rabbit Anti-SIRT3/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-SIRT3/FITC Conjugated antibody

hSIRT3; hSIRT 3; hSIRT3; Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase; NAD dependent deacetylase sirtuin 3 mitochondrial; NAD-dependent deacetylase sirtuin-3, mitochondrial; Silent mating type information regulation 2 S.cerevisiae

Cat:

SL6105R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Human,Dog,Pig,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human SIRT3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

43kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

Function:
NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

Subunit:
Interacts with NDUFA9, ACSS1, IDH2 and GDH.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
Processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product. Such processing is probably essential for its enzymatic activity.

Similarity:
Belongs to the sirtuin family. Contains 1 deacetylase sirtuin-type domain.

Database links:

Entrez Gene: 23410 Human

Entrez Gene: 64384 Mouse

Omim: 604481 Human

SwissProt: Q9NTG7 Human

SwissProt: Q8R104 Mouse

Unigene: 716456 Human

Unigene: 244216 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall