background:
The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein.
Function:
Seems to have an immune potentiation function
Subunit:
Interacts with PRKCD and with phosphatidylserine. Phosphatidylserine may form a bridge between PKC and PKSLCbinding partners and stabilize the binding
Tissue Specificity:
Strongly expressed in mammary and epithelial cells.
Post-translational modifications:
In vitro, phosphorylated by PRKCD.
Similarity:
Belongs to the PTRF/SDPR family.
Database links:
Entrez Gene: 112464 Human
Entrez Gene: 109042 Mouse
Entrez Gene: 85332 Rat
SwissProt: A4FV37 Cow
SwissProt: Q969G5 Human
SwissProt: Q91VJ2 Mouse
SwissProt: Q9Z1H9 Rat
Unigene: 434044 Human
Unigene: 3124 Mouse
Unigene: 12281 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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