background:
LEPREL2 belongs to a family of collagen prolyl hydroxylases required for proper collagen biosynthesis, folding, and assembly.
Function:
Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types IV and V (By similarity).
Subcellular Location:
Endoplasmic reticulum.
Tissue Specificity:
Weak expression in heart, lung, ovary and skeletal muscle.
Similarity:
Belongs to the leprecan family.
Contains 1 Fe2OG dioxygenase domain.
Contains 4 TPR repeats.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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