Rabbit Anti-EXTL2/FITC Conjugated antibody

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Alpha 1 4 N acetylhexosaminyltransferase EXTL2; Alpha GalNAcT EXTL2; Exostoses (multiple) like 2; Exostoses multiple like 2; Exostosin like 2; EXT L2; EXT related protein 2; EXTL 2; EXTR 2; EXTR2; Glucuronyl galactosyl proteoglycan 4 alpha N acetylglucosa

Cat:

SL6005R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human EXTL

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

37kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and is responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

Function:
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type II membrane protein .
Processed exostosin-like 2: Secreted. Note=A soluble form is found in the serum.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing.

Similarity:
Belongs to the glycosyltransferase 47 family.

Database links:

Entrez Gene: 2135 Human

Entrez Gene: 58193 Mouse

GenBank: BC045681 Human

Omim: 602411 Human

SwissProt: Q9UBQ6 Human

SwissProt: Q9ES89 Mouse

Unigene: 357637 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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