Home > Product > Antibody > Rabbit Anti-l-Myc/FITC Conjugated antibody
l myc protein; l myc 1 proto oncogene; L myc 1 proto-oncogene protein; Myc related gene from lung cancer; MYCL 1; MYCL1; MYCL; MYCL1; LMYC; BHLHE38; Protein L-Myc-1; oncogene lmyc; v myc avian myelocytomatosis viral oncogene homolog 1 lung carcinoma deriv
Cat:
SL5979R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human MYCL1 (266-315aa)
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
40kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis. The MYCL1 gene encodes a protein which is associated with lung cancer in idiopathic pulmonary fibrosis.

Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an heterodimer with MAX.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.

Database links:

Entrez Gene: 4610 Human

Entrez Gene: 16918 Mouse

Entrez Gene: 298506 Rat

Omim: 164850 Human

SwissProt: P12524 Human

SwissProt: P10166 Mouse

Unigene: 437922 Human

Unigene: 1055 Mouse

Unigene: 479066 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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