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Rabbit Anti-l-Myc/FITC Conjugated antibody
background:
Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis. The MYCL1 gene encodes a protein which is associated with lung cancer in idiopathic pulmonary fibrosis.
Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an heterodimer with MAX.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Database links:
Entrez Gene: 4610 Human
Entrez Gene: 16918 Mouse
Entrez Gene: 298506 Rat
Omim: 164850 Human
SwissProt: P12524 Human
SwissProt: P10166 Mouse
Unigene: 437922 Human
Unigene: 1055 Mouse
Unigene: 479066 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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