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Rabbit Anti-c-Myb/FITC Conjugated antibody
background:
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Function:
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Subcellular Location:
Nucleus.
Post-translational modifications:
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.
Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.
Similarity:
Contains 3 HTH myb-type DNA-binding domains.
Database links:
Entrez Gene: 317776 Cow
Entrez Gene: 922 Human
Entrez Gene: 17863 Mouse
Entrez Gene: 498982 Rat
Omim: 189990 Human
SwissProt: P46200 Cow
SwissProt: P10242 Human
SwissProt: P06876 Mouse
Unigene: 60664 Human
Unigene: 52109 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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