background:
SSX8 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas.
Function:
Could act as a modulator of transcription.
Tissue Specificity:
Not detected in any normal or tumor tissues.
Similarity:
Belongs to the SSX family.
Contains 1 KRAB-related domain.
Database links:
UniProtKB/Swiss-Prot: Q7RTT4.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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