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Rabbit Anti-Fast Myosin Skeletal Heavy chain/FITC Conjugated antibody
background:
Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008].
Function:
Muscle contraction.
Subunit:
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLSLC2).
Subcellular Location:
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.
Database links:
Entrez Gene: 281337 Cow
Entrez Gene: 4619 Human
Entrez Gene: 17879 Mouse
Entrez Gene: 287408 Rat
Omim: 160730 Human
Omim: 160740 Human
SwissProt: Q9BE40 Cow
SwissProt: P12882 Human
SwissProt: Q5SX40 Mouse
SwissProt: Q9TV61 Pig
Unigene: 689619 Human
Unigene: 477065 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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