Rabbit Anti-MMP-23/FITC Conjugated antibody

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Cysteine array matrix metalloproteinase; Femalysin; Matrix metallopeptidase 21; Matrix metallopeptidase 23A (pseudogene); Matrix metallopeptidase 23A; Matrix metallopeptidase 23B; Matrix metalloproteinase 22; Matrix metalloproteinase 23; Matrix metallopro

Cat:

SL5875R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human MMP-23

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

36/44kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Matrix Metalloproteinase 23 is a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region.

Function:
Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type II membrane protein (By similarity). Membrane; Single-pass type II membrane protein. Note=A secreted form produced by proteolytic cleavage may also exist (Probable).

Tissue Specificity:
Predominantly expressed in ovary, testis and prostate.

Post-translational modifications:
N-glycosylated.
Proteolytic cleavage might yield an active form (By similarity).

Similarity:
Belongs to the peptidase M10A family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 8510 Human

Entrez Gene: 26561 Mouse

Entrez Gene: 94339 Rat

Omim: 603321 Human

SwissProt: O75900 Human

SwissProt: O88676 Mouse

SwissProt: O88272 Rat

Unigene: 192316 Human

Unigene: 671760 Human

Unigene: 29373 Mouse

Unigene: 22562 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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