background:
DCBLD2, otherwise known as ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a novel type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. DCBLD2 is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells.
Similarity:
Contains 1 CUB domain.
Contains 1 F5/8 type C domain.
Contains 1 LCCL domain.
Database links:
Entrez Gene: 131566 Human
Entrez Gene: 73379 Mouse
Entrez Gene: 155696 Rat
Omim: 608698 Human
SwissProt: Q96PD2 Human
SwissProt: Q91ZV3 Mouse
SwissProt: Q91ZV2 Rat
Unigene: 203691 Human
Unigene: 373589 Mouse
Unigene: 157411 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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