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Rabbit Anti-RAIDD/FITC Conjugated antibody
background:
Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
Subunit:
Interacts with LRDD.
Tissue Specificity:
Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
Similarity:
Contains 1 CARD domain.
Contains 1 death domain.
Database links:
Entrez Gene: 8738 Human
Entrez Gene: 12905 Mouse
Entrez Gene: 314756 Rat
Omim: 603454 Human
SwissProt: P78560 Human
SwissProt: O88843 Mouse
Unigene: 38533 Human
Unigene: 591016 Human
Unigene: 473739 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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