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Rabbit Anti-NUAK2/FITC Conjugated antibody
background:
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.
Similarity:
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Database links:
Entrez Gene: 81788 Human
Entrez Gene: 74137 Mouse
Omim: 608131 Human
SwissProt: Q9H093 Human
SwissProt: Q8BZN4 Mouse
Unigene: 497512 Human
Unigene: 100666 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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