Rabbit Anti-NR2F1 + NR2F2/FITC Conjugated antibody

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Apolipoprotein AI regulatory protein 1; ARP1; COUP TF1; COUP TF2; COUP transcription factor 2; Chicken ovalbumin upstream promoter 1; COT1_HUMAN; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP-TF1; EAR-3; EAR3; ERBAL3; NR2F1; NR

Cat:

SL5782R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human NR2F2.

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

46kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
NR2F2 is involved in the regulation of the apolipoprotein A-I gene transcription. It binds to DNA site A as a homodimer. It belongs to the nuclear hormone receptor family, NR2 subfamily. It has roles in angiogenesis, vascular remodeling and heart development.

Function:
Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG.

Subunit:
Binds DNA as dimer; homodimer and probable heterodimer with NR2F6. Interacts with COPS2.

Subcellular Location:
Nucleus (Probable).

Similarity:
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Contains 1 nuclear receptor DNA-binding domain

Database links:

Entrez Gene: 281945 Cow

Entrez Gene: 7026 Human

Entrez Gene: 11819 Mouse

Entrez Gene: 113984 Rat

Omim: 107773 Human

SwissProt: Q9TTR7 Cow

SwissProt: P24468 Human

SwissProt: P43135 Mouse

SwissProt: O09018 Rat

Unigene: 347991 Human

Unigene: 17815 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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