Rabbit Anti-Adenylate cyclase 1/FITC Conjugated antibody

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3'5' cyclic AMP synthetase; ADCY1; adenyl cyclase; Adenylate cyclase 1; adenylate cyclase type I; ATP pyrophosphate lyase; Brain adenylate cyclase 1; Ca(2+)/calmodulin activated adenylyl cyclase; EC 4.6.1.1; ADCY1_HUMAN; Adenylate cyclase type 1; ATP pyro

Cat:

SL4288R-FITC

Species Reactivity：

Rat,(predicted: Human,Mouse,Dog,Pig,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human Adenylate cyclase 1.

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

123kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The membrane bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein coupled receptors. Eight human AC isoforms (ASLC1 through ASLC4) have been identified up to now and genes for at least nine adenylate cyclase (ASLC1-ASLC9) have been cloned characterized and sequenced. This is a calmodulin-sensitive adenylyl cyclase which may be involved in regulatory processes in the central nervous system. It may play a role in neuronal plasticity, memory acquisition and learning and is expressed predominantly in the brain, retina and adrenal medulla.

Function:
This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Brain, retina and adrenal medulla.

Similarity:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.

Database links:

Entrez Gene: 107 Human

Entrez Gene: 432530 Mouse

Entrez Gene: 305509 Rat

Omim: 103072 Human

SwissProt: Q08828 Human

SwissProt: O88444 Mouse

Unigene: 192215 Human

Unigene: 259733 Mouse

Unigene: 214145 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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