Rabbit Anti-Fetuin A/AHSG/FITC Conjugated antibody

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Fetuin-A; 59 kDa bone sialic acid containing protein; A2HS; Aa2 066; AHS; AHSG; Alpha 2 HS glycoprotein; Alpha 2 HS glycoprotein chain A; Alpha 2 Z globulin; Alpha 2HS glycoprotein; alpha2 Heremans Schmid glycoprotein; Asialofetuin; Ba alpha 2 glycoprotei

Cat:

SL2922R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human Alpha-2-HS-glycoprotein chain A.

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

31/40kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008]

Function:
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

Subunit:
Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond.

Subcellular Location:
Secreted.

Tissue Specificity:
Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.

Similarity:
Belongs to the fetuin family.
Contains 2 cystatin fetuin-A-type domains.

Database links:

Entrez Gene: 197 Human

Entrez Gene: 26998 Human

Omim: 138136 Human

Omim: 605954 Human

SwissProt: P02765 Human

SwissProt: Q9UGM5 Human

Unigene: 324746 Human

Unigene: 81073 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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