Rabbit Anti-FGF22/FITC Conjugated antibody

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FGF 22; FGF-22; FGF22; FGF22_HUMAN; Fibroblast growth factor 22; si:dkey 21e2.2.

Cat:

SL5773R-FITC

Species Reactivity：

(predicted: Human,Mouse,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human FGF22.

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

17kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
FGF22 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Fibroblast Growth Factor-22 stimulates the proliferation and activation of cells that express FGF receptor.

Function:
Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.

Subunit:
Interacts with FGFR1 and FGFR2. Interacts with FGFBP1.

Subcellular Location:
Secreted (Potential).

Similarity:
Belongs to the heparin-binding growth factors family.

Database links:

Entrez Gene: 27006 Human

Entrez Gene: 67112 Mouse

Entrez Gene: 170579 Rat

Omim: 605831 Human

SwissProt: Q9HCT0 Human

SwissProt: Q9ESS2 Mouse

Unigene: 49687 Human

Unigene: 154211 Mouse

Unigene: 198777 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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