Rabbit Anti-CDC40/FITC Conjugated antibody

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Cell division cycle 40 homolog; EH binding protein 3; Ehb3; Pre mRNA processing factor 17; PRP17; PRP17 homolog; PRPF17; PRP17_HUMAN; Pre-mRNA-processing factor 17; EH-binding protein 3; hPRP17.

Cat:

SL4295R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human CDC40

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

64kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]

Function:
Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.

Subunit:
Identified in the spliceosome C complex.

Subcellular Location:
Nucleus.

Similarity:
Contains 7 WD repeats.

Database links:

Entrez Gene: 51362 Human

Entrez Gene: 71713 Mouse

Entrez Gene: 361859 Rat

Omim: 605585 Human

SwissProt: O60508 Human

SwissProt: Q9DC48 Mouse

Unigene: 428147 Human

Unigene: 9263 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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