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Rabbit Anti-APRIL/TNFSF13/FITC Conjugated antibody
background:
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Function:
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Subunit:
Homotrimer (Potential).
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Post-translational modifications:
The precursor is cleaved by furin.
Similarity:
Belongs to the tumor necrosis factor family.
Database links:
Entrez Gene: 8741 Human
Entrez Gene: 69583 Mouse
Entrez Gene: 287437 Rat
Omim: 604472 Human
SwissProt: O75888 Human
SwissProt: Q9D777 Mouse
Unigene: 54673 Human
Unigene: 8983 Mouse
Unigene: 19955 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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