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Home > Product > Antibody > Rabbit Anti-CCDC106/FITC Conjugated antibody
Ccdc106; Coiled-coil domain-containing protein 106; Protein predicted by clone 23882; ZNF581; CC106_HUMAN.
Cat:
SL5711R-FITC
Species Reactivity：
(predicted: Human,Mouse,Rat,Dog,Cow,Horse,)
Immunogen：
KLH conjugated synthetic peptide derived from human CCDC106
Format：
Lyophilized or Liquid
Storage instructions：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer：
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Calculated MW：
31kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Promotes the degradation of p53/TP53 protein and inhibits its transactivity.

Function:
Promotes the degradation of p53/TP53 protein and inhibits its transactivity.

Subunit:
Interacts with p53/TP53.

Subcellular Location:
Nucleus. Note=Colocalizes with p53/TP53.

Database links:

Entrez Gene: 29903 Human

Entrez Gene: 232821 Mouse

Entrez Gene: 499071 Rat

Omim: 613478 Human

SwissProt: Q9BWC9 Human

SwissProt: Q3ULM0 Mouse

Unigene: 82482 Human

Unigene: 482157 Mouse

Unigene: 488775 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CCDC106通过与p53蛋白相互作用，促进p53蛋白的降解，导致p53功能失活。CCDC106基因很可能是一个癌基因，CCDC106的高表达可能是导致具有野生型p53肿瘤发生的原因之一。
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