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Home > Product > Antibody > Rabbit Anti-CDKN2AIP/FITC Conjugated antibody
Calcium response factor; CARF; CDKN2A interacting protein; CDKN2AIP; ALS2CR8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; CaRF; Testis development protein NYD-SP24; AL2S8_HUMAN.
Cat:
SL4267R-FITC
Species Reactivity：
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)
Immunogen：
KLH conjugated synthetic peptide derived from human CARF
Format：
Lyophilized or Liquid
Storage instructions：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer：
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Calculated MW：
80kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
CARF was first cloned as a novel binding partner of ARF from a yeast interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.

Function:
May be a transcription factor.

Subcellular Location:
Nucleus (Potential).

Database links:

Entrez Gene: 461623 Chimpanzee

Entrez Gene: 513265 Cow

Entrez Gene: 607991 Dog

Entrez Gene: 55602 Human

Entrez Gene: 70925 Mouse

Entrez Gene: 100513762 Pig

Entrez Gene: 306455 Rat

SwissProt: Q8TBM5 Human

SwissProt: Q9NXV6 Human

SwissProt: Q8BI72 Mouse

SwissProt: Q8VHI4 Mouse

SwissProt: Q5U2X0 Rat

Unigene: 68877 Human

Unigene: 393807 Mouse

Unigene: 16007 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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