Rabbit Anti-MACC1/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-MACC1/FITC Conjugated antibody

7A5; MACC1; MACC-1; MACC1_HUMAN; Metastasis associated in colon cancer 1; Metastasis-associated in colon cancer protein 1; Putative binding protein 7a5; SH3 domain-containing protein 7a5; SH3BP4L.

Cat:

SL4293R-FITC

Species Reactivity：

Human,Rat,(predicted: Mouse,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human MACC1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

94kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
MACC1 is a key regulator of the hepatocyte growth factor(HGF; MIM 14489)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed19098908]).[supplied by OMIM].

Subunit:
Interacts with FASLG.

Subcellular Location:
Cytoplasm. Nucleus. Note=Mainly found in the cytoplasm in non-metastasizing tumors.

Tissue Specificity:
Preferentially expressed in metastasizing tumors.

Similarity:
Contains 1 SH3 domain.

Database links:

Entrez Gene: 346389 Human

Entrez Gene: 238455 Mouse

Entrez Gene: 314539 Rat

Omim: 612646 Human

SwissProt: Q6ZN28 Human

Unigene: 598388 Human

Unigene: 31376 Mouse

Unigene: 81938 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall