background:
P2RX3 is a member of the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and transduces ATP-evoked nociceptor activation. P2RX3 is important for peripheral pain responses, and controls urinary bladder volume reflexes.
Function:
Receptor for ATP that acts as a ligand-gated ion channel.
Subunit:
Homo- or heteropolymers.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the P2X receptor family.
Database links:
Entrez Gene: 5024 Human
Entrez Gene: 228139 Mouse
Entrez Gene: 81739 Rat
Omim: 600843 Human
SwissProt: P56373 Human
SwissProt: Q3UR32 Mouse
SwissProt: P49654 Rat
Unigene: 146738 Human
Unigene: 88375 Mouse
Unigene: 448935 Mouse
Unigene: 10388 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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