Home > Product > Antibody > Rabbit Anti-VAPA/FITC Conjugated antibody
VAMP A; VAMP associated protein A; VAP 33; VAP A; VAP33; Vesicle associated membrane protein associated protein A; VAPA_HUMAN.
Cat:
SL4226R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Cow,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human VAPA
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
28kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
VAPA is a type IV membrane protein, present in the plasma membrane, intracellular vesicles and may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Two transcript variants encoding distinct isoforms have been identified.

Function:
May play a role in vesicle trafficking.

Subunit:
Homodimer, and heterodimer with VAPB. Interacts with VAMP1, VAMP2, STX1A, BET1, SEC22C and with the SLCterminal domain of OCLN. Interacts with OSBPL1A. Interacts (via MSP domain) with ZFYVE27; may retain ZFYVE27 in the endoplasmic reticulum and regulate its function in cell projections formation.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. Contains 1 MSP domain.

Database links:
UniProtKB/Swiss-Prot: Q9P0L0.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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