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Rabbit Anti-phospho-14-3-3 epsilon (Thr232)/FITC Conjugated antibody
background:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Subunit:
Homodimer. Heterodimerizes with YWHAZ. Interacts with NDEL1, RGNEF and TIAM2. Interacts with HCV core protein. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Weakly interacts with CDKN1B. Interacts with GAB2. Interacts with phosphorylated GRB10. Interacts with PKA-phosphorylated AANAT. Interacts with the phosphorylated (by AKT1) form of SRPK2.
Subcellular Location:
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Similarity:
Belongs to the 14-3-3 family.
Database links:
Entrez Gene: 7531 Human
Entrez Gene: 282125 Cow
Entrez Gene: 22627 Mouse
Entrez Gene: 29753 Rat
Omim: 605066 Human
SwissProt: P62261 Cow
SwissProt: P62258 Human
SwissProt: P62259 Mouse
SwissProt: P62260 Rat
Unigene: 513851 Human
Unigene: 234700 Mouse
Unigene: 471625 Mouse
Unigene: 4225 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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