Rabbit Anti-phospho-14-3-3 epsilon (Thr232)/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-phospho-14-3-3 epsilon (Thr232)/FITC Conjugated antibody

YWHAE(phospho T232); 14-3-3 epsilon (phospho Thr232); 14-3-3 epsilon; 14 3 3 E; 14 3 3 epsilon; 14 3 3E; 14-3-3 E; 14-3-3 protein epsilon; 14-3-3E; 14-3-3ε; 1433E_HUMAN; KCIP 1; KCIP-1; KCIP1; MDCR; MDS; mitochondrial import stimulation factor L subunit;

Cat:

SL5590R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Cow,Sheep,)

Immunogen：

KLH conjugated Synthesised phosphopeptide derived from human 14-3-3E around the phosphorylation site of Thr232

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

Flow-Cyt=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

29kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Subunit:
Homodimer. Heterodimerizes with YWHAZ. Interacts with NDEL1, RGNEF and TIAM2. Interacts with HCV core protein. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Weakly interacts with CDKN1B. Interacts with GAB2. Interacts with phosphorylated GRB10. Interacts with PKA-phosphorylated AANAT. Interacts with the phosphorylated (by AKT1) form of SRPK2.

Subcellular Location:
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Similarity:
Belongs to the 14-3-3 family.

Database links:

Entrez Gene: 7531 Human

Entrez Gene: 282125 Cow

Entrez Gene: 22627 Mouse

Entrez Gene: 29753 Rat

Omim: 605066 Human

SwissProt: P62261 Cow

SwissProt: P62258 Human

SwissProt: P62259 Mouse

SwissProt: P62260 Rat

Unigene: 513851 Human

Unigene: 234700 Mouse

Unigene: 471625 Mouse

Unigene: 4225 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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