Rabbit Anti-MSS1/FITC Conjugated antibody

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26S protease complex; mammalian suppressor of sgv-1 of yeast; MSS1; Nbla10058; protease 26S subunit 7; proteasome 26S ATPase subunit 2; Proteasome 26S subunit ATPase 2; proteasome 26S subunit ATPase 2; Protein MSS1; PSMC2; putative protein product of Nbla

Cat:

SL5120R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human MSS1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

48kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes and the endoplasmic reticulum.

Function:
he 26S protease is involved in the ATP-dependentdegradation of ubiquitinated proteins. The regulatory (or ATPase)complex confers ATP dependency and substrate specificity to the 26Scomplex. In case of HISLV1 infection, positive modulator ofTat-mediated transactivation.

Subunit:
Interacts with NDC80 and SQSTM1. Interacts with PAAF1.Interacts with HISLV1 Tat.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the AAA ATPase family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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