Home
>
Product
>
Antibody
>
Rabbit Anti-IGFBP6/FITC Conjugated antibody
background:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Function:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Subcellular Location:
Secreted.
Post-translational modifications:
O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylated on one site only in the region AA 143-168 in cerebrospinal fluid.
Similarity:
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.
Database links:
Entrez Gene: 3489 Human
Entrez Gene: 16012 Mouse
Entrez Gene: 25641 Rat
Omim: 146735 Human
SwissProt: P24592 Human
SwissProt: P47176 Mouse
SwissProt: P35572 Rat
Unigene: 274313 Human
Unigene: 358609 Mouse
Unigene: 6431 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|