Home > Product > Antibody > Rabbit Anti-ME1/FITC Conjugated antibody
Cytosolic malic enzyme 1; HUMNDME; Malate dehydrogenase; Malic enzyme 1; Malic enzyme 1, NADP(+) dependent, cytosolic; Malic enzyme 1, soluble; Malic enzyme, cytoplasmic; MES; NADP dependent malic enzyme; NADP ME; Pyruvic malic carboxylase.Cytosolic malic
Cat:
SL5084R-FITC
Species Reactivity:
Rat,(predicted: Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human NADP ME
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
64kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
ME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in all tissues tested including liver, placenta and white adipose tissue.

Similarity:
Belongs to the malic enzymes family.

Database links:

Entrez Gene: 4199 Human

Entrez Gene: 17436 Mouse

Entrez Gene: 24552 Rat

Omim: 154250 Human

SwissProt: P48163 Human

SwissProt: P01361 Mouse

SwissProt: P13697 Rat

Unigene: 21160 Human

Unigene: 148155 Mouse

Unigene: 3519 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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