Rabbit Anti-LASS6/FITC Conjugated antibody

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T1L; CerS 6; CerS6; LAG1 homolog ceramide synthase 6; LAG1 longevity assurance homolog 6; LASS 6; Longevity assurance homolog 6; MGC129949; MGC129950; CERS6_HUMAN.

Cat:

SL5080R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human LASS6

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The LASS (longevity-assurance homologue) family members, which are highly conserved among eukaryotes, function in ceramide synthesis. LASS6 (LAG1 homolog, ceramide synthase 6) may be involved in sphingolipid synthesis or its regulation.

Function:
May be involved in sphingolipid synthesis or its regulation

Subcellular Location:
Nucleus membrane; Multi-pass membrane protein (Potential). Endoplasmic reticulum membrane; Multi-pass membrane protein

Post-translational modifications:
Glycosylation on Asn-18 is not necessary for function

Similarity:
Contains 1 homeobox DNA-binding domain.
Contains 1 TLC (TRAM/LAG1/CLN8) domain.

Database links:

Entrez Gene: 253782 Human

Entrez Gene: 241447 Mouse

Entrez Gene: 366065 Rat

SwissProt: Q6ZMG9 Human

SwissProt: Q8C172 Mouse

Unigene: 506829 Human

Unigene: 724377 Human

Unigene: 222222 Mouse

Unigene: 393211 Mouse

Unigene: 8190 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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