Rabbit Anti-Ceramide synthase 1/FITC Conjugated antibody

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CerS1; LAG1; LASS1; LAG1 homolog ceramide synthase 1; LAG1 longevity assurance homolog 1; LASS 1; Longevity assurance (LAG1 S. cerevisiae) homolog 1; Longevity assurance gene 1; MGC90349; Protein LAG1; UOG 1 protein; UOG1; Upstream of GDF1; Ceramide synth

Cat:

SL5076R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,.,)

Immunogen：

KLH conjugated synthetic peptide derived from human LASS1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

39kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
LASS1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells it is involved in the production of sphingolipids containing mainly one fatty acid donnor in a fumonisin B1-independent manner.

Function:
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Isoform 1: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Isoform 1 may recycle from the Golgi to the endoplasmic reticulum.

Similarity:
Contains 1 TLC (TRAM/LAG1/CLN8) domain.

Database links:

Entrez Gene: 10715 Human

Omim: 606919 Human

SwissProt: P27544 Human

Unigene: 412355 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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