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Rabbit Anti-FABP4/FITC Conjugated antibody
background:
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq].
Function:
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Subunit:
Monomer. Homodimer. Interacts with PPARG.
Subcellular Location:
Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Database links:
Entrez Gene: 2167 Human
Entrez Gene: 11770 Mouse
Entrez Gene: 79451 Rat
Omim: 600434 Human
SwissProt: P15090 Human
SwissProt: P04117 Mouse
SwissProt: P70623 Rat
Unigene: 391561 Human
Unigene: 582 Mouse
Unigene: 4258 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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