Home > Product > Antibody > Rabbit Anti-CYP4A22/FITC Conjugated antibody
CYP4A22; CYPIVA22; Cytochrome P450 4A22; Cytochrome P450 4A22K; Cytochrome P450 family 4 subfamily A polypeptide 22; Fatty acid omega hydroxylase; Lauric acid omega hydroxylase; RP1 18D14.1; CP4AM_HUMAN.
Cat:
SL5055R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human CYP4A22
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
58kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
Cytochrome P450 4A22 (CYP4A22) is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.

Function:
Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Shows no activity towards arachidonic acid and prostaglandin A1. Lacks functional activity in the kidney and does not contribute to renal 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis.

Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Microsome membrane; Peripheral membrane protein

Similarity:
Belongs to the cytochrome P450 family.

Database links:

Entrez Gene: 284541 Human

GenBank: NM_001010969 Human

Omim: 615341 Human

SwissProt: Q5TCH4 Human

Unigene: 726474 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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