Home > Product > Antibody > Rabbit Anti-CYP4A1/FITC Conjugated antibody
20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; CP4AB_HUMAN; Cyp4a1; Cyp4a10; CYP4A11; Cyp4a14; Cyp4a3; CYP4A7; CYP4AII; CYPIVA11; Cytochrome P-450HK-omega; Cytochrome P450 4A1; Cytochrome P450 4A10; Cytochrome P450 4A11; Cytochrome P450 4A14;
Cat:
SL5054R-FITC
Species Reactivity:
Human,Mouse,(predicted: Rat,Dog,Pig,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human CYP4A1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
59kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. [provided by RefSeq, Jul 2008].

Function:
Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).

Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Tissue Specificity:
Kidney and liver.

Similarity:
Belongs to the cytochrome P450 family.

Database links:

Entrez Gene: 1579 Human

Entrez Gene: 24306 Rat

Entrez Gene: 298423 Rat

Entrez Gene: 50549 Rat

Omim: 601310 Human

SwissProt: Q02928 Human

SwissProt: P14581 Rabbit

SwissProt: P08516 Rat

SwissProt: P20816 Rat

SwissProt: P20817 Rat

Unigene: 1645 Human

Unigene: 726474 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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