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Rabbit Anti-ACOX2/FITC Conjugated antibody
background:
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq, Mar 2009]
Function:
Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids.
Subunit:
Heterodimer
Subcellular Location:
Peroxisome.
Tissue Specificity:
Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.
Similarity:
Belongs to the acyl-CoA oxidase family
Database links:
Entrez Gene: 8309 Human
Entrez Gene: 514969 Cow
Entrez Gene: 93732 Mouse
Entrez Gene: 252898 Rat
Omim: 601641 Human
SwissProt: Q99424 Human
SwissProt: Q9QXD1 Mouse
SwissProt: O02767 Rabbit
SwissProt: P97562 Rat
Unigene: 444959 Human
Unigene: 28700 Mouse
Unigene: 10622 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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