Rabbit Anti-SOAT2/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-SOAT2/FITC Conjugated antibody

Acat2; acetoacetyl CoA thiolase; acetoacetyl Coenzyme A thiolase; Acetyl CoA acetyltransferase; Acetyl CoA transferase like protein; acetyl Coenzyme A acetyltransferase 2; Acetyl-CoA acetyltransferase; Acetyl-CoA transferase-like protein; Acyl Coenzyme A

Cat:

SL5020R-FITC

Species Reactivity：

Human,Rat,(predicted: Mouse,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human ACAT2 (355-400aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

60kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.

Function:
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.

Subunit:
May form homo- or heterodimers (By similarity).

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Similarity:
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.

Database links:

Entrez Gene: 8435 Human

Omim: 601311 Human

SwissProt: O75908 Human

Unigene: 20580 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall