background:
Zinc is an essential cofactor for more than 50 classes of enzymes and is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, plus the control of gene transcription, growth, development, and differentiation. Zinc cannot passively diffuse across cell membranes and requires specific transporters, such as SLC39A7, to enter the cytosol from both the extracellular environment and from intracellular storage compartments.
Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).
Tissue Specificity:
Major expression in placenta, lung, kidney and pancreas.
Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
Database links:
UniProtKB/Swiss-Prot: Q92504.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|